How must the symbol indicating the schedule of a controlled substance be presented on a label?

The schedule symbol indicating the classification of a controlled substance must be displayed clearly and prominently on the label. Presenting the symbol two times the size of the largest print on the label ensures that the classification is easily recognizable to practitioners, pharmacists, and patients. This prominence is essential for ensuring the safe handling and dispensing of controlled substances, as it alerts individuals about the potential for abuse, addiction, or adverse effects associated with these medications.

In contrast, standard font size might not provide adequate visibility, while using bold italics or varying colors might not guarantee that the information is immediately clear and distinct. The requirement for the schedule indication to be twice the size of the largest text serves as a uniform standard for ensuring that critical safety information is not overlooked.